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Tenofovir disoproxil fumarate Tenofovir
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te-NOE-fo-veer dye soe PROX il   Audio

Brand Name: Viread  Audio
Drug Class: Nucleoside Reverse Transcriptase Inhibitors
Tenofovir disoproxil fumarate (tenofovir DF), also known as Viread, is a type of medicine called a nucleoside reverse transcriptase inhibitor (NRTI). NRTIs block reverse transcriptase, a protein that HIV needs to make more copies of itself. Tenofovir DF is also approved for the treatment of hepatitis B virus in adults.

HIV/AIDS-Related Uses
Tenofovir DF was approved by the FDA on October 26, 2001, for use in combination with other antiretroviral agents in the treatment of HIV infections in adults. This medicine does not cure or prevent HIV infection or AIDS and does not reduce the risk of passing the virus to other people.

Dosage Form/Administration
Tenofovir DF comes in tablet form and is taken by mouth.


Recommended Daily Dose
The recommended dose of tenofovir DF is 300 mg once a day. Individuals with decreased kidney function may need to take tenofovir DF less often. Some individuals may benefit from different doses of tenofovir DF. Individuals should always take tenofovir DF as prescribed by their doctors.

Contraindications
Individuals should tell a doctor about any medical problems before taking this medicine.

Possible Side Effects
Along with its desired effects, tenofovir DF may cause some unwanted effects. Serious side effects of this medicine include liver or kidney failure and severe disease of the pancreas. Symptoms may include abdominal pain; decreased appetite; diarrhea; fast, shallow breathing; general feeling of discomfort; muscle pain or cramping; nausea; shortness of breath; sleepiness; unusual tiredness or weakness; and vomiting. Individuals should tell a doctor if they have any of these symptoms.
Other side effects may not be serious and may lessen or disappear with continued use of the medicine. Less serious side effects of this medicine include abdominal discomfort, diarrhea, dizziness, intestinal gas, headache, and rash. Individuals should tell a doctor if these side effects continue or are bothersome.

Drug and Food Interactions
A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.

Clinical Trials
Click here to search ClinicalTrials.gov for trials that use Tenofovir disoproxil fumarate.

Manufacturer Information
Viread
  Gilead Sciences Inc
  333 Lakeside Dr
  Foster City,  CA  94404
  (800) 445-3235
    

Tenofovir disoproxil fumarate
  Gilead Sciences Inc
  333 Lakeside Dr
  Foster City,  CA  94404
  (800) 445-3235
    
Updated December 27, 2007