Kaletra can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), heart rhythm problems, severe allergic reactions, and life-threatening drug interactions.
Contact your health care provider right away if you have any of the following symptoms that may signal liver problems:
Contact your health care provider right away if you have any of the following symptoms that may signal pancreatitis:
Contact your health care provider right away if you have any of the following symptoms that may signal heart rhythm problems:
Contact your health care provider right away if you develop a skin rash. This could be a sign of a severe allergic reaction.
Babies taking Kaletra oral solution may have side effects. (Kaletra oral solution contains alcohol and propylene glycol.) Contact your health care provider right away if your baby appears too sleepy or his/her breathing has changed.
Taking Kaletra with certain other medicines may result in serious and/or life-threatening side effects.
While taking Kaletra, it is important to keep all of your appointments with your health care provider.
Kaletra is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 14 days of age and older. Kaletra is always used in combination with other HIV medicines.
Kaletra contains the following two different medicines combined in one pill:
PIs block an HIV enzyme called protease. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking protease, the two drugs in combination prevent HIV from multiplying and can reduce the amount of HIV in the body.
Kaletra does not cure HIV/AIDS. People with HIV should stay on continuous HIV treatment as directed by their health care provider and should take steps to avoid passing HIV to others (for example, always using a condom during sex).
Before taking Kaletra, tell your health care provider:
Kaletra comes in the following forms and strengths:
Take Kaletra according to your health care provider’s instructions. If your child is prescribed Kaletra, tell your doctor if your child’s weight changes.
Kaletra tablets can be taken with or without food and should be swallowed whole. Do not chew, break, or crush the tablets.
Take Kaletra oral solution with food.
If you are also taking the HIV medicine didanosine (brand name: Videx; Videx EC):
Always take Kaletra in combination with other HIV medicines.
If you take too much Kaletra, contact your health care provider or local poison control center (1-800-222-1222) right away or go to the nearest hospital emergency room.
For more information on how to take Kaletra, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
Take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
Kaletra can cause serious, life-threatening side effects. These include liver problems, pancreatitis (inflammation of the pancreas), heart rhythm problems, severe allergic reactions, and life-threatening drug interactions. (See the WARNING above.)
Other possible side effects of Kaletra include:
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Kaletra. Ask your health care provider or pharmacist for more information on possible side effects of Kaletra. You may also want to read this fact sheet about HIV medicines and side effects.
More information about Kaletra is available:
Last Reviewed: April 3, 2014
Last Updated: April 3, 2014