Dolutegravir can cause serious, life-threatening side effects. These include allergic reactions.
Contact your health care provider right away if you have a rash.
Stop taking dolutegravir and get medical help right away if you have a rash with any of the following symptoms:
Stop taking dolutegravir and get medical help right away if you have any of the following symptoms that may signal liver problems:
Do not take dolutegravir if you take dofetilide. Taking dolutegravir and dofetilide can cause side effects that may be life threatening.
While taking dolutegravir, it is important to keep all of your appointments with your health care provider.
Dolutegravir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 12 years of age and older and weighing at least 88 pounds (40 kilograms). Dolutegravir is always used in combination with other HIV medicines.
Dolutegravir is a type of HIV medicine called an integrase inhibitor. Dolutegravir works by blocking integrase, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood.
Dolutegravir does not cure HIV/AIDS. It is not known if dolutegravir reduces the risk of passing HIV to other people.
Before taking dolutegravir, tell your health care provider:
Dolutegravir comes in tablet form. Each tablet contains 50 mg dolutegravir (brand name: Tivicay).
Take dolutegravir according to your health care provider’s instructions.
Take dolutegravir by mouth, with or without food. Do not change your dose or stop taking dolutegravir without talking with your health care provider first.
Always take dolutegravir in combination with other HIV medicines.
If you take too much dolutegravir, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room right away.
For more information on how to take dolutegravir, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
Take the missed dose as soon as you remember it. But if it is within 4 hours of your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
Dolutegravir can cause serious, life-threatening side effects. These include allergic reactions. (See the WARNING above.)
Other possible side effects of dolutegravir include:
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of dolutegravir. Ask your health care provider or pharmacist for more information on side effects of dolutegravir.
More information about dolutegravir is available:
Last Reviewed: May 22, 2014
Last Updated: May 22, 2014