A Service of U.S. Department of Health and Human Services

Home > Drugs > Fluconazole

Non-Technical Version

HIV/AIDS-Related Uses Dosage Information Contraindications Possible Side Effects Drug and Food Interactions Clinical Trials Manufacturer Information Non-Technical version in PDF

Fluconazole floo-KOE-na-zole Brand Name: Diflucan Drug Class: Opportunistic Infection and Other Drugs Fluconazole, also known as Diflucan, belongs to the class of medicines called antifungals. Antifungals kill fungi or stop fungi from multiplying or spreading. When fungal infections occur in individuals with weakened immune systems, including people with HIV, they tend to be more serious and are called opportunistic infections (OIs).    HIV/AIDS-Related Uses Fluconazole can be used to both prevent and treat certain types of fungal infections, especially those that occur as OIs in immunocompromised individuals with HIV.    Dosage Information Fluconazole comes in tablet and oral suspension forms taken by mouth and in liquid form that is generally given by intravenous infusion into a vein. The intravenous infusion form is usually reserved for more severe fungal infections.    Contraindications Individuals should tell a doctor about any medical problems before taking this medicine.    Possible Side Effects Along with its desired effects, fluconazole may cause some unwanted effects. Such adverse effects include fever and chills; skin rash or itching; sore throat; reddening, blistering, peeling, or loosening of skin and mucous membranes; dark or amber urine; loss of appetite; pale stools; stomach pain; unusual tiredness or weakness; yellow eyes or skin; and unusual bleeding or bruising. Individuals should tell a doctor if they have any of these side effects. Other side effects may not be serious and may lessen or disappear with continued use of this medicine. Less serious side effects of this medicine include dizziness, drowsiness, headache, abdominal pain, constipation, diarrhea, nausea, and vomiting. Individuals should tell a doctor if these side effects continue or are bothersome.    Drug and Food Interactions A doctor should be notified of any other medications being taken, including prescription, nonprescription (over-the-counter), or herbal medications.    Clinical Trials Click here to search ClinicalTrials.gov for trials that use Fluconazole.    Manufacturer Information Fluconazole     Pfizer Inc     235 East 42nd Street     New York, NY, 10017-5755     (800) 438-1985   Diflucan     Pfizer Inc     235 East 42nd Street     New York, NY, 10017-5755     (800) 438-1985

Updated May 16, 2008.