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Issue No. 20  | May 13, 2011
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AIDSinfo.nih.gov is pleased to provide you with a weekly update of highlights about what has happened in the world of HIV/AIDS treatment, prevention, and research. We hope you find this encapsulated view of HIV/AIDS news useful.

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NIAID Study Suggests Treating HIV-Infected People with Antiretrovirals Reduces the Risk of Transmitting HIV to Sexual Partners

“Men and women infected with HIV reduced the risk of transmitting the virus to their sexual partners by taking oral antiretroviral medicines when their immune systems were relatively healthy … .

“The clinical trial, known as HPTN 052, was slated to end in 2015 but the findings are being released early as the result of a scheduled interim review of the study data by an independent data and safety monitoring board (DSMB). … The results are the first from a major randomized clinical trial to indicate that treating an HIV-infected individual can reduce the risk of sexual transmission of HIV to an uninfected partner. …

“HPTN 052 began in April 2005 and enrolled 1,763 couples … . The vast majority of the couples (97 percent) were heterosexual, which precludes any definitive conclusions about effectiveness in men who have sex with men. …

“The investigators randomly assigned the couples to either one of two study groups. In the first group, the HIV-infected partner immediately began taking a combination of three antiretroviral drugs. In the second group (the deferred group), the HIV-infected partners began antiretroviral therapy when their CD4 counts fell below 250 cells/mm³ or an AIDS-related event, such as Pneumocystis pneumonia, occurred. …

“In its review, the DSMB found a total of 39 cases of HIV infection among the previously uninfected partners. Of those, 28 were linked through genetic analysis to the HIV-infected partner as the source of infection. … Of the 28 linked infections, 27 infections occurred among the 877 couples in which the HIV-infected partner did not begin antiretroviral therapy immediately. Only one case of HIV infection occurred among those couples where the HIV-infected partner began immediate antiretroviral therapy. This finding was statistically significant and means that earlier initiation of antiretrovirals led to a 96 percent reduction in HIV transmission to the HIV-uninfected partner.”

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Join AIDSinfo in Observing HIV Vaccine Awareness Day

May 18, 2011, marks the 14th annual observance of HIV Vaccine Awareness Day, a day that provides an opportunity to recognize the volunteers, community members, health professionals, and scientists working together toward finding an HIV vaccine. This day is also an opportunity to educate communities across the United States about the importance of HIV vaccine research.

AIDSinfo has developed a specialty page for this awareness day with information and resources about HIV vaccine research.
 
More information is available:


Join AIDSinfo in Observing National Asian and Pacific Islander HIV/AIDS Awareness Day

May 19, 2011, marks the seventh annual National Asian and Pacific Islander HIV/AIDS Awareness Day, a day that serves to increase awareness of HIV/AIDS in the Asian and Pacific Islander communities. According to the 2009 HIV Surveillance Report from the Centers for Disease Control and Prevention (CDC), in the 40 states with confidential name-based HIV reporting, from 2006 to 2009 the rate of new HIV diagnoses has increased among Asians and decreased among Pacific Islanders.

AIDSinfo has developed a specialty page for this awareness day with information and resources about HIV/AIDS and the Asian and Pacific Islander communities.

More information is available:


CDC Updates HIV Surveillance by Race/Ethnicity Slide Set

The Centers for Disease Control and Prevention (CDC) recently updated the HIV Surveillance by Race/Ethnicity slide set with information from the 2009 HIV Surveillance Report. The slide set provides information on HIV diagnoses in the United States and dependent areas, broken down by race/ethnicity.


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ISSN 1558-3228