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Clinical Trials

MainTitle

Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients

This study has been completed
Sponsor
University of Southern California


Information provided by (Responsible Party)
NIH AIDS Clinical Trials Information Service
ClinicalTrials.gov Identifier
NCT00002052

First received: November 2, 1999
Last updated: June 23, 2005
Last Verified: August 1989
History of Changes
Purpose

Purpose

To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in AIDS patients.

Condition Intervention
HIV Infections
Salmonella Infections

Drug : Ceftriaxone sodium
Drug : Ampicillin sodium
Drug : Amoxicillin trihydrate

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients

Further study details as provided by NIH AIDS Clinical Trials Information Service:

Eligibility

Eligibility

Ages Eligible for Study: 18 Years and older  
Sexes Eligible for Study: All  
Accepts Healthy Volunteers: No  

Criteria

Exclusion Criteria
Co-existing Condition:
Patients with the following are excluded:

  • Type I hypersensitivity to beta-lactam antibiotics.
  • Not expected to survive 12 weeks.
  • In a coma or with other central nervous system (CNS) impairment.

  • Patients with the following are excluded:
  • Type I hypersensitivity to beta-lactam antibiotics.
  • Not expected to survive 12 weeks.
  • In a coma or with other central nervous system (CNS) impairment.

  • Prior Medication:
    Excluded within 48 hours of study entry:
  • Treatment with an antibiotic active in vitro against Salmonella.

  • HIV infection, AIDS, or AIDS related complex (ARC).
  • Salmonella bacteremia or positive stool culture in patient with 3 or more stools per
day.

contacts and locations

Contacts and Locations

Choosing to participate in a study is an important personal decision.Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT00002052

Locations

United States, California
Los Angeles County - USC Med Ctr
Los Angeles, California, United States, 90033

Sponsors and Collaborators

University of Southern California
More Information

More Information


Responsible Party: University of Southern California  
ClinicalTrials.gov Identifier: NCT00002052   History of Changes  
Other Study ID Numbers: 019A  
Study First Received: November 2, 1999  
Last Updated: June 23, 2005  

Keywords provided by NIH AIDS Clinical Trials Information Service:

Salmonella Infections
AIDS-Related Opportunistic Infections
Acquired Immunodeficiency Syndrome
Amoxicillin
Ceftriaxone

Additional relevant MeSH terms:
Infection
Communicable Diseases
HIV Infections
Salmonella Infections
Amoxicillin
Ceftriaxone
Ampicillin

ClinicalTrials.gov processed this data on October 20, 2017
This information is provided by ClinicalTrials.gov.