Clinical Trials


Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

This study has been completed
Palo Alto Medical Foundation

Information provided by (Responsible Party)
NIH AIDS Clinical Trials Information Service Identifier

First received: November 2, 1999
Last updated: June 23, 2005
Last Verified: June 1989
History of Changes


To compare pyrimethamine and intravenous (IV) clindamycin vs. pyrimethamine and sulfonamides in the treatment of AIDS patients with central nervous system (CNS) Toxoplasma gondii.

Condition Intervention
Toxoplasmosis, Cerebral
HIV Infections

Drug : Pyrimethamine
Drug : Clindamycin

Study Type: Interventional
Study Design: Primary Purpose: Treatment
Official Title: Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of Relapse

Further study details as provided by NIH AIDS Clinical Trials Information Service:



Ages Eligible for Study: 18 Years and older  
Sexes Eligible for Study: All  
Accepts Healthy Volunteers: No  


Exclusion Criteria
Co-existing Condition:
Patients with the following conditions are excluded:

  • Opportunistic infection (Pneumocystis carinii pneumonia (PCP), cryptococcal
meningitis) or other conditions (brain abscess) which would make treatment results difficult to interpret due to concurrent infection, disease, or therapy.
Patients with other opportunistic infections or brain diseases are excluded.
Patients with AIDS and cerebral toxoplasmosis.

contacts and locations

Contacts and Locations

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Please refer to this study by its identifier: NCT00002064


United States, California
Palo Alto Med Foundation
Palo Alto, California, United States, 94301

Sponsors and Collaborators

Palo Alto Medical Foundation
More Information

More Information

Responsible Party: Palo Alto Medical Foundation Identifier: NCT00002064   History of Changes  
Other Study ID Numbers: 021A  
Study First Received: November 2, 1999  
Last Updated: June 23, 2005  

Keywords provided by NIH AIDS Clinical Trials Information Service:

AIDS-Related Opportunistic Infections
Drug Therapy, Combination
Acquired Immunodeficiency Syndrome

Additional relevant MeSH terms:
Toxoplasmosis, Cerebral
Clindamycin palmitate
Clindamycin phosphate
Pyrimethamine processed this data on June 01, 2020
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