Clinical Trials

MainTitle

Neighborhoods, Networks, Depression, and HIV Risk (Workshop)

This study has been completed
Sponsor
Johns Hopkins Bloomberg School of Public Health

Collaborator
National Institute on Drug Abuse (NIDA)

Information provided by (Responsible Party)
Carl Latkin, Johns Hopkins Bloomberg School of Public Health

ClinicalTrials.gov Identifier
NCT01380613

First received: March 7, 2011
Last updated: September 4, 2013
Last Verified: September 2013
History of Changes
Purpose

Purpose

The goal of this study is to examine how social networks, neighborhood, and depression are related to HIV risk. The intervention is designed to train individuals to cope with feelings of depression or stress as a way to reduce their risk for HIV.

Condition Intervention Phase
HIV
Depression
Drug Use

Behavioral : Workshop
Behavioral : Workshop control
Phase 2

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: The Impact of Neighborhoods, Networks, and Depression on Drug Users' HIV Risk

Further study details as provided by Carl Latkin, Johns Hopkins Bloomberg School of Public Health:

Primary Outcome Measures

  • Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 6 months [ Time Frame: 6 months ]
  • Change from Baseline in Depressive Symptoms Measured by the CESD Scale at 12 months [ Time Frame: 12 months ]
Secondary Outcome Measures:
  • Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 6 months [ Time Frame: 6 months ]
  • Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 6 months [ Time Frame: 6 months ]
  • Change from Baseline in Sex Risk Behavior Based on Number of Sex Partners and Condom Use at 12 months [ Time Frame: 12 months ]
  • Change from Baseline in Injection Risk Behavior Based on Sharing Needles, Cookers, and Cotton For Injection and Drug Splitting at 12 months [ Time Frame: 12 months ]

Enrollment: 965
Study Start Date: September 2007
Study Completion Date: July 2013
Primary Completion Date: July 2013 (Final data collection date for primary outcome measure)

Arms Assigned Interventions
Active Comparator: Workshop Control
Participants receive HIV/STDs risk reduction information.
Behavioral: Workshop control

1 session intervention on standard HIV/STD information

Experimental: Intervention Workshop
Participants learn skills to cope with depressive symptoms and stress as well as safer sex and injection skills.
Behavioral: Workshop

10 session intervention

Detailed Description:

This study included implementation and evaluation of a small group, randomized controlled, phase II intervention to reduce depressive symptoms and HIV risk behaviors among inner city drug users. The intervention included elements of cognitive behavioral therapy (CBT) for depression among impoverished individuals, emphasizing depressive cognitions and behaviors theorized to be associated with depression and with HIV risk behaviors among mildly to moderately depressed drug users. In addition, the study examined active drug users' social and environmental pathways to depression and subsequent HIV risk behaviors. Specifically, we will hypothesized mediating/moderating effects of neighborhood characteristics, social network factors, and individual level factors on depressive symptoms and HIV risk behaviors.

Eligibility

Eligibility

Ages Eligible for Study: 18 Years to 55 Years  
Sexes Eligible for Study: All  
Accepts Healthy Volunteers: No  

Criteria

Inclusion Criteria:

    1. 18-55 years old
    2. HIV Risk Behavior:

    3a. Injected drugs more than 3 times in the past week OR

3b. Snorted/sniffed heroin or cocaine or smoked crack in the past 6 months AND had 1 of the following sex risks in the past 6 months: i) 2 or more sex partners ii) Had a sex partner who injected drugs iii)Had a sex partner who smoked crack iv) Had a sex partner who was HIV+
  • Willingness to attend group sessions


  • Exclusion Criteria:
      1. Enrolled in another HIV behavioral intervention or depression study in past the 3 years
      2. Enrolled in another Lighthouse study in past the 5 years
      3. Enrolled in the formative research (Phase 1) or pilot (Phase 2) of the current
      project.

    contacts and locations

    Contacts and Locations

    Choosing to participate in a study is an important personal decision.Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.For general information, see Learn About Clinical Studies.

    Please refer to this study by its ClinicalTrials.gov identifier: NCT01380613

    Locations

    United States, Maryland
    Lighthouse Studies @ Peer Points- JHSPH
    Baltimore, Maryland, United States, 21205

    Sponsors and Collaborators

    Johns Hopkins Bloomberg School of Public Health
    National Institute on Drug Abuse (NIDA)

    Investigators

    Principal Investigator: Carl A Latkin, PhD Johns Hopkins Bloomberg School of Public Health
    More Information

    More Information


    Responsible Party: Carl Latkin, Professor, Johns Hopkins Bloomberg School of Public Health  
    ClinicalTrials.gov Identifier: NCT01380613   History of Changes  
    Other Study ID Numbers: DESPR-DA022961-03  
      R01DA022961  
    Study First Received: March 7, 2011  
    Last Updated: September 4, 2013  

    Keywords provided by Carl Latkin, Johns Hopkins Bloomberg School of Public Health:

    HIV
    depression
    drug use,
    risk reduction

    Additional relevant MeSH terms:
    Depression
    Depressive Disorder

    ClinicalTrials.gov processed this data on December 15, 2017
    This information is provided by ClinicalTrials.gov.