Clinical Trials


Advanced HIV Prevention (PrEP Chicago)

This study is ongoing, but not recruiting participants.
University of Chicago

Information provided by (Responsible Party)
University of Chicago Identifier

First received: July 26, 2016
Last updated: December 5, 2018
Last Verified: December 2018
History of Changes


This study will evaluate the feasibility of a network intervention to train individuals to disseminate PrEP information and motivate initial PrEP interest and knowledge of PrEP in their social networks.

Condition Intervention

Behavioral : PrEP Intervention Group
Other : Control Group

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Advanced HIV Prevention (PrEP Chicago)

Further study details as provided by University of Chicago:

Primary Outcome Measures

  • Network member call into the PrEPline [ Time Frame: 2 years ]
Secondary Outcome Measures:
  • PrEP Attitudes questionnaire [ Time Frame: 2 years ]
    Monitor the change in attitude towards PrEP (1) from baseline measure to 12-months; (2) 12-months to 24-months; and (3) baseline to 24-month.
  • Peer change agent boosters sessions completed [ Time Frame: 2 years ]
  • Number of Facebook posts with respect to PrEP and sexual health [ Time Frame: 2 years ]
  • Number of referrals enrolled into the study [ Time Frame: 2 years ]

Enrollment: 424
Study Start Date: March 2016
Estimated Study Completion Date: March 2020
Estimated Primary Completion Date: March 2019 (Final data collection date for primary outcome measure)

Arms Assigned Interventions
Experimental: PrEP Intervention Group
Group training session including HIV Education, PrEP Education, Following the training session Booster phone calls HIv and syphillis testing
Behavioral: PrEP Intervention Group
Active Comparator: Control Group
Group HIV risk vignettes
Other: Control Group

Detailed Description:

The specific aims of this study are:

  1. To recruit 240 participants in Chicago, Illinois, and to train them as peer change agents (randomized to cross-over groups) to disseminate PrEP information and motivate PrEP interest and knowledge of PrEP in their local networks.
  2. To evaluate feasibility of the program over 2 years of participant follow-up through: 1)
peer change agent exit survey; 2) peer change agent booster sessions; 3) peer change agent communication with University of Chicago PrEP program social media; 4) referrals into the project and; 5) calls into the PrEP warmline.



Ages Eligible for Study: 18 Years to 39 Years  
Sexes Eligible for Study: Male  
Accepts Healthy Volunteers: Yes  


Inclusion Criteria:

  • Lives on the South Side of Chicago, Illinois
  • Born male
  • Has had sex with men in the previous year
  • Is an active Facebook user
  • Does not have plans to leave Chicago

Exclusion Criteria:

contacts and locations

Contacts and Locations

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Please refer to this study by its identifier: NCT02896699


United States, Illinois
University of Chicago Medical Center
Chicago, Illinois, United States, 60637

Sponsors and Collaborators

University of Chicago
More Information

More Information

Responsible Party: University of Chicago Identifier: NCT02896699   History of Changes  
Other Study ID Numbers: IRB15-1250  
Study First Received: July 26, 2016  
Last Updated: December 5, 2018  
Individual Participant Data    
Plan to Share IPD: No  

Keywords provided by University of Chicago:

Pre-exposure prophylaxis (PrEP)
diffusion of innovation
men who have sex with men
African American
network analysis
network intervention processed this data on August 19, 2019
This information is provided by