Elvitegravir can cause changes in the immune system (immune reconstitution inflammatory syndrome [IRIS]).
Elvitegravir must be taken with a protease inhibitor HIV medicine along with the HIV medicine ritonavir (brand name: Norvir) and with other HIV medicine(s).
Do not take elvitegravir if you are taking cobicistat (brand name: Tybost) with a protease inhibitor or if you are taking other medicines that contain elvitegravir (for example, Stribild).
While taking elvitegravir, it is important to keep all of your appointments with your health care provider.
Elvitegravir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults who are already taking or have taken HIV medicines before. Elvitegravir is always used in combination with other HIV medicines.
Elvitegravir belongs to a class (group) of HIV drugs called integrase inhibitors. Integrase inhibitors block an HIV enzyme called integrase. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body.
HIV medicines can’t cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission. If you are taking HIV medicines, including elvitegravir, don’t cut down on, skip, or stop taking them unless your health care provider tells you to.
Before taking elvitegravir, tell your health care provider:
Elvitegravir (brand name: Vitekta) comes in tablet form in two strengths:
Take elvitegravir according to your health care provider’s instructions.
Take elvitegravir with food. Elvitegravir must be taken with a protease inhibitor HIV medicine along with the HIV medicine ritonavir (brand name: Norvir) and with other HIV medicine(s). Talk to your health care provider about the HIV medicines you are taking.
If you take too much elvitegravir, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.
For more information on how to take elvitegravir, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
If you miss a dose of elvitegravir, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
Elvitegravir can cause serious side effects, including immune reconstitution inflammatory syndrome (IRIS). IRIS is a condition that sometimes occurs when the immune system begins to recover after treatment with an HIV medicine. As the immune system gets stronger, it may have an increased response to a previously hidden infection. (See the WARNING above.)
The most common side effect of elvitegravir is diarrhea.
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of elvitegravir. To learn more about possible side effects of elvitegravir, read the drug label or package insert or talk to your health care provider or pharmacist.
The AIDSinfo fact sheet on HIV Medicines and Side Effects also includes information that may apply to elvitegravir.
You can also report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online at https://www.accessdata.fda.gov/scripts/medwatch/.
More information about elvitegravir is available:
Gilead Sciences, Inc.
Last Reviewed: August 19, 2015