MiconazoleOther Names: Oravig Drug Class: Opportunistic Infections and Coinfections
What is miconazole?
Miconazole is anprescription medicine approved by the U.S. (FDA) for the treatment of oropharyngeal , a fungal infection of the part of the throat at the back of the mouth. Oropharyngeal candidiasis is a type of candidiasis.
Oropharyngeal candidiasis is an What is an Opportunistic Infection? fact sheet.(OI) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the
How is miconazole used in people with HIV?
The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents include recommendations on the uses of miconazole in people with HIV.
Using a medicine as indicated on the medicine label is called; using the medicine in a different way is called . Off-label use, for example, can include using a drug for a different disease or medical condition. Good medical practice and the best interests of a patient sometimes require that a medicine be used off-label.
The guidelines include recommendations on the on-label use of miconazole to treat oropharyngeal candidiasis and the off-label use of the drug to treat uncomplicated vulvovaginal candidiasis. Vulvovaginal candidiasis is a type of mucocutaneous candidiasis that affects the vulva and the vagina (parts of the female genitalia).The above may not include all of the HIV-related uses of miconazole recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. Some recommended uses, such as uses in certain rare circumstances, may have been omitted.
What should I tell my health care provider before taking miconazole?
Before taking miconazole, tell your health care provider:
- If you are allergic to miconazole, milk concentrate or any other ingredient in miconazole, or any other medicines.
- About any medical conditions you have or have had, for example, or problems.
- About anything that could affect your ability to take medicines, such as difficulty swallowing or remembering to take pills.
- If you are pregnant or plan to become pregnant. Whether miconazole can harm an unborn baby is unknown. Miconazole should not be used during pregnancy unless the potential benefit to the mother outweighs the potential risk to the . Talk to your health care provider about possible risks with taking miconazole when pregnant.
- If you are breastfeeding or plan to breastfeed. Do not breastfeed if you have HIV.
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Miconazole may affect the way other medicines or products work, and other medicines or products may affect how miconazole works. Ask your health care provider if there are interactions between miconazole and the other medicines you take.
Ask your health care provider about possible side effects from miconazole. Your health care provider will tell you what to do if you have side effects.
How should I take miconazole?
Take miconazole according to your health care provider’s instructions. Your health care provider will tell you how much miconazole to take and when to take it. Before you start miconazole and each time you get a refill, read any printed information that comes with your medicine.
How should miconazole be stored?
- Store miconazole tablets at room temperature, 68°F to 77°F (20°C to 25°). Protect the tablets from moisture.
- Keep miconazole in the container that it came in and keep the container tightly closed.
- Do not use miconazole if the original seal over the container opening is broken or missing.
- Throw away miconazole that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
- Keep miconazole and all medicines out of reach of children.
Where can I find more information about miconazole?
More information about miconazole is available:
- Recommendations on the HIV-related uses of miconazole, from the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the , the , and the HIV Medicine Association of the Diseases Society of America
- Miconazole-related research studies, from the AIDSinfo database of study summaries
The above Patient Version drug summary is based on the following FDA label(s): Tablet.
Last Reviewed: February 20, 2019