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AIDSinfo Drug Database

AIDSinfo Drug Database

Drugs by class



Terconazole  Audio icon

Other Names: Terazol 3, Terazol 7
Drug Class: Opportunistic Infections and Coinfections

Chemical Image:
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Molecular Weight: 532.4689

What is terconazole?

Terconazole is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of vulvovaginal candidiasis, which is an infection of the female vulva and vagina and is a type of mucocutaneous candidiasis.

Mucocutaneous candidiasis is a fungal infection that is caused by Candida yeasts and affects the skin and mucous membranes (such as in the mouth or vagina). Mucocutaneous candidiasis (also called mucosal candidiasis) is an opportunistic infection. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as those infected with HIV—than in people with healthy immune systems. To learn more about opportunistic infections, read the AIDSinfo What is an Opportunistic Infection? fact sheet.

The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), includes recommendations on the HIV-related use of terconazole to treat uncomplicated vulvovaginal candidiasis.

The above may not include all of the HIV-related uses of terconazole recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. Some recommended uses, such as uses in certain rare circumstances, may have been omitted.

What should I tell my health care provider before taking terconazole?

Before taking terconazole, tell your health care provider:

  • If you are allergic to terconazole or any other medicines.
  • About any medical conditions you have or have had, for example, diabetes or liver problems. 
  • About anything that could affect your ability to take medicines, such as difficulty with remembering when to take medicines.
  • If you are pregnant or plan to become pregnant. Terconazole should not be used in the first trimester of pregnancy unless your health care provider considers it essential for your health. Talk to your health care provider about possible risks with taking terconazole when pregnant.
  • If you are breastfeeding or plan to breastfeed. Do not breastfeed if you are infected with HIV.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Terconazole may affect the way other medicines or products work, and other medicines or products may affect how terconazole works. Ask your health care provider if there are interactions between terconazole and the other medicines you take.

Ask your health care provider about possible side effects from terconazole. Your health care provider will tell you what to do if you have side effects.

How should I take terconazole?

Take terconazole according to your health care provider’s instructions. Your health care provider will tell you how much terconazole to take and when to take it. Before you start terconazole and each time you get a refill, read any printed information that comes with your medicine.

How should terconazole be stored?

  • Store terconazole vaginal cream (0.4% and 0.8%) (brand names: TERAZOL® 7 and TERAZOL® 3) and vaginal suppositories (brand name: TERAZOL® 3) at room temperature, 59°F to 86°F (15°C to 30°C).
  • Store terconazole vaginal cream (0.8%) (generic formulation manufactured by E. Fougera & Co.) at room temperature, 68°F to 77°F (20°C to 25°C). 
  • Do not use terconazole if the original seal over the container opening is broken or missing.
  • Throw away terconazole that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
  • Keep terconazole and all medicines out of reach of children.

Where can I find more information about terconazole?

More information about terconazole is available:

The above Patient Version drug summary is based on the following FDA label(s): Cream (0.4% and 0.8%), suppository; Cream (0.8%).

Last Reviewed: November 7, 2016

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