Flucytosine is an antifungal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of serious infections caused by certain types of two different fungi: Candida and Cryptococcus.
Cryptococcosis, which is an infection caused by the Cryptococcus fungus, is an opportunistic infection. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as those infected with HIV—than in people with healthy immune systems.
The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), includes recommendations on the HIV-related use of flucytosine to treat cryptococcosis.
The above list may not include all of the HIV-related uses of flucytosine recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. Some recommended uses, such as uses in certain rare circumstances, may have been omitted.
Before taking flucytosine, tell your health care provider:
Ask your health care provider about possible side effects from flucytosine. Your health care provider will tell you what to do if you have side effects.
Take flucytosine according to your health care provider’s instructions. Your health care provider will tell you how much flucytosine to take and when to take it. Before you start flucytosine and each time you get a refill, read any printed information that comes with your medicine.
More information about flucytosine is available:
Last Reviewed: April 13, 2015