Sinecatechins is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of external genital warts (warts on the outside of the genitals) and external perianal warts (warts around the outside of the anus) in immunocompetent people. (Immunocompetent means having an immune system that can fight off infections normally.) Sinecatechins’ safety and effectiveness in immunosuppressed people is unknown. (Immunosuppressed means having an immune system that cannot fight off infections as well as it should.) Sinecatechins is a topical ointment, which means that it is for skin use only.
External genital warts and perianal warts are caused by the human papillomavirus (HPV). HPV is an opportunistic infection. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as those infected with HIV—than in people with healthy immune systems.
The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), include recommendations on the HIV-related use of sinecatechins to treat external genital and perianal warts caused by HPV.
The above paragraph may not include all of the HIV-related uses of sinecatechins recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. Some recommended uses, such as uses in certain rare circumstances, may have been omitted.
Before taking sinecatechins, tell your health care provider:
Ask your health care provider about possible side effects from sinecatechins. Your health care provider will tell you what to do if you have side effects.
Take sinecatechins according to your health care provider’s instructions. Your health care provider will tell you how much sinecatechins to take and when to take it. Before you start sinecatechins and each time you get a refill, read any printed information that comes with your medicine.
More information about sinecatechins is available:
Last Reviewed: June 1, 2015