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AIDSinfo Drug Database

AIDSinfo Drug Database

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FDA-approved

Investigational

Sinecatechins  Audio icon

Other Names: Veregen
Drug Class: Opportunistic Infections and Coinfections
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Chemical Image:
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sinecatechins
sinecatechins
Molecular Weight: 471.4357

What is sinecatechins?

Sinecatechins is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of external genital warts (warts on the outside of the genitals) and external perianal warts (warts around the outside of the anus) in immunocompetent people. (Immunocompetent means having an immune system that can fight off infections normally.) Sinecatechins’ safety and effectiveness in immunosuppressed people is unknown. (Immunosuppressed means having an immune system that cannot fight off infections as well as it should.) Sinecatechins is a topical ointment, which means that it is for skin use only.

External genital warts and perianal warts are caused by the human papillomavirus (HPV). HPV is an opportunistic infection. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as those infected with HIV—than in people with healthy immune systems.

What HIV-related opportunistic infections is sinecatechins used for?

The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), include recommendations on the HIV-related use of sinecatechins to treat external genital and perianal warts caused by HPV.

The above paragraph may not include all of the HIV-related uses of sinecatechins recommended in the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents. Some recommended uses, such as uses in certain rare circumstances, may have been omitted.

What should I tell my health care provider before taking sinecatechins?

Before taking sinecatechins, tell your health care provider:

  • If you are allergic to sinecatechins or any other medicines.
  • About any medical conditions you have or have had, for example, diabetes or liver problems. 
  • Whether you are using any other type of skin product or have open wounds on the area to be treated. Sinecatechins should not be used until your skin has healed from other treatments applied to the same area.
  • Whether you are immunocompromised (your immune system cannot fight infections as well as it should).
  • About anything that could affect your ability to use sinecatechins, such as difficulty with applying an ointment to the affected area or trouble with remembering a scheduled dose
  • If you are pregnant or plan to become pregnant. Whether sinecatechins can harm an unborn baby is unknown. Sinecatechins should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Talk to your health care provider about possible risks with taking sinecatechins when pregnant.
  • If you are breastfeeding or plan to breastfeed. Do not breastfeed if you are infected with HIV.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Sinecatechins may affect the way other medicines or products work, and other medicines or products may affect how sinecatechins works. Ask your health care provider if there are interactions between sinecatechins and the other medicines you take.

Ask your health care provider about possible side effects from sinecatechins. Your health care provider will tell you what to do if you have side effects.

How should I take sinecatechins?

Take sinecatechins according to your health care provider’s instructions. Your health care provider will tell you how much sinecatechins to take and when to take it. Before you start sinecatechins and each time you get a refill, read any printed information that comes with your medicine.

How should sinecatechins be stored?

  • Store sinecatechins ointment in the refrigerator or up to 77°F (25°C). Do not freeze it.
  • Make sure the cap on the tube is tightly closed.
  • Throw away sinecatechins that is no longer needed or expired (out of date). Follow FDA guidelines on how to safely dispose of unused medicine.
  • Keep sinecatechins and all medicines out of reach of children.

Where can I find more information about sinecatechins?

More information about sinecatechins is available:

The above Patient Version drug summary is based on the following FDA label(s): Ointment.

Last Reviewed: June 1, 2015

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