Hepatitis B VaccineOther Names: Engerix-B, HBV vaccine, Heplisav-B, Recombivax HB, hepatitis B vaccine, hepatitis B vaccine (recombinant), hepatitis b vaccine (recombinant) adjuvanted Drug Class: Opportunistic Infections and Coinfections
What is a hepatitis B vaccine?
HBV is an (OI) of HIV. An OI is an that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the What is an Opportunistic Infection? fact sheet. To learn how HIV and HBV infection are connected, read the AIDSinfo HIV and Hepatitis B fact sheet.
The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV include recommendations on the use of hepatitis B vaccines in people with HIV.
What should I tell my health care provider before receiving a hepatitis B vaccine?
Before receiving a hepatitis B vaccine, tell your health care provider:
- If you are allergic to yeast, any other ingredient in a hepatitis B vaccine, or any medicines. Tell your health care provider if you have ever had any reactions to a previous of a hepatitis B vaccine.
- About any medical conditions you have or have had.
- If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of getting a hepatitis B vaccine during pregnancy.
- If you are breastfeeding or plan to breastfeed. Do not breastfeed if you have HIV.
- About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Hepatitis B vaccines may affect the way other medicines or products work, and other medicines or products may affect how hepatitis B vaccines work. Ask your health care provider if there are interactions between hepatitis B vaccines and the medicines you take.
Ask your health care provider about possible side effects from getting a hepatitis B vaccine. Your health care provider will tell you what to do if you have side effects.
How is a hepatitis B vaccine given?
A health care provider gives the hepatitis B vaccine. Engerix-B and Recombivax HB are both approved for use in people of all ages. Heplisav-B is approved for use in adults 18 years of age and older. The vaccine is given as a shot injected into a muscle, usually in the arm for adults and children older than 1 year and in the thigh for infants and children younger than 1 year.with a hepatitis B vaccine is usually given as a series of injections over a period of time, depending on the specific brand of the vaccine. Read any printed information that your health care provider gives you about the hepatitis B vaccine.
Where can I find more information about hepatitis B vaccines?
More information about hepatitis B vaccines is available:
- Recommendations on the use of hepatitis B vaccines in people living with HIV, from the Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV, prepared by the , the , and the HIV Medicine Association of the Diseases Society of America
- Hepatitis B vaccine-related research studies, from the AIDSinfo database of study summaries
Last Reviewed: March 27, 2020