Viekira Pak is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of chronic (lasting a long time) hepatitis C virus (HCV) infection, including in people with a certain type of liver damage called compensated cirrhosis. Viekira Pak includes two different types of tablets. One tablet contains the medicines ombitasvir, paritaprevir, and ritonavir. The other tablet contains the medicine dasabuvir.
HCV is an opportunistic infection. An opportunistic infection is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as those infected with HIV—than in people with healthy immune systems.
The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), and the Hepatitis C Guidance: AASLD-IDSA Recommendations for Testing, Managing, and Treating Adults Infected with Hepatitis C Virus, prepared by the American Association for the Study of Liver Diseases (AASLD), the Infectious Diseases Society of America (IDSA), and the International Antiviral Society-USA (IAS-USA), both include recommendations on the HIV-related use of Viekira Pak to treat chronic HCV infection.
In addition to recommendations for the medicine's use in treating chronic HCV infection, the guidelines and the guidance include recommendations on the “off-label” use of Viekira Pak to treat acute HCV infection in HIV-infected individuals. “Off-label” use refers to use of an FDA-approved medicine in a manner different from that described on the medicine label. Good medical practice and the best interests of a patient sometimes require that a medicine be used “off-label.”
Before taking Viekira Pak, tell your health care provider:
Ask your health care provider about possible side effects from Viekira Pak. Your health care provider will tell you what to do if you have side effects.
Take Viekira Pak according to your health care provider’s instructions. Your health care provider will tell you how much of Viekira Pak to take and when to take it. Before you start Viekira Pak and each time you get a refill, read any printed information that comes with your medicine. If you take the medicine ribavirin along with Viekira Pak, also read any printed information that comes with your ribavirin medicine.
More information about Viekira Pak is available:
Last Reviewed: May 19, 2016