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AIDSinfo Drug Database

AIDSinfo Drug Database

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Human Papillomavirus Bivalent (types 16 and 18) Vaccine, Recombinant  Audio icon

Brand Name: Cervarix
Other Names: HPV recombinant vaccine bivalent, bivalent HPV vaccine
Drug Class: Opportunistic Infections and Coinfections

What is Cervarix?

Cervarix is a vaccine approved by the U.S. Food and Drug Administration (FDA) to help protect against cervical cancer and precancers caused by human papillomavirus (HPV) types 16 and 18. There are many types of HPV but only certain types cause cervical cancer. HPV types 16 and 18 are the two most common types of HPV that lead to cervical cancer and precancers. 
Cervarix is approved for use by girls and women 9 through 25 years of age.

The Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents, prepared by the Centers for Disease Control and Prevention (CDC), the National Institutes of Health (NIH), and the HIV Medicine Association of the Infectious Diseases Society of America (IDSA-HIVMA), includes recommendations on the use of Cervarix in HIV-infected individuals. 

What should I tell my health care provider before receiving Cervarix?

Before receiving Cervarix, tell your health care provider:

  • If you are allergic to latex, any ingredients in Cervarix, or any medicines. Tell your health care provider if you have ever had any reactions to a previous dose of the vaccine or to any other HPV vaccine. 
  • About any medical conditions you have or have had, for example, diabetes or liver problems. 
  • If you are pregnant or plan to become pregnant Cervarix is not recommended for use in pregnant women. 
  • If you are breastfeeding or plan to breastfeed. Do not breastfeed if you are infected with HIV. 
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Cervarix may affect the way other medicines or products work, and other medicines or products may affect how Cervarix works. Ask your health care provider if there are interactions between Cervarix and the medicines you take. 

Ask your health care provider about possible side effects from Cervarix. Your health care provider will tell you what to do if you have side effects.

How is Cervarix given?

A health care provider gives the Cervarix vaccine. The vaccine is given as an injection (shot) in a muscle in your arm. Vaccination with Cervarix is usually given as a series of 3 vaccine shots over a 6-month period. Read any printed information that your health care provider gives you about the HPV vaccine. 

Where can I find more information about HPV vaccines?

More information about HPV vaccines is available:

The above Patient Version drug summary is based on the following FDA label(s): Injection (suspension).

Last Reviewed: September 11, 2015

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