Contact your health care provider right away if you have any of the following symptoms that could be signs of lactic acidosis:
Contact your health care provider right away if you have any of the following symptoms that could be signs of liver problems:
Descovy is not approved for the treatment of chronic hepatitis B virus (HBV) infection. If you have both HIV and HBV infection and take Descovy, your HBV infection may get much worse (flare up) if you stop taking Descovy.
While taking Descovy, it is important to keep all of your appointments with your health care provider.
Descovy is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 12 years of age and older who weigh at least 77 pounds (35 kilograms). Descovy is always used in combination with other HIV medicines.
Descovy contains the following two different medicines combined in one tablet:
NRTIs block an HIV enzyme called reverse transcriptase. (An enzyme is a protein that starts or increases the speed of a chemical reaction.) By blocking reverse transcriptase, the two drugs in combination prevent HIV from multiplying and can reduce the amount of HIV in the body.
HIV medicines can’t cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission.
Before taking Descovy, tell your health care provider:
Descovy comes in tablet form. Each tablet contains:
Take Descovy according to your health care provider’s instructions.
Take Descovy once each day with or without food.
Always take Descovy in combination with other HIV medicines.
If you take too much Descovy, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.
For more information on how to take Descovy, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
If you miss a dose of Descovy, contact your health care provider.
Descovy may cause side effects. Most side effects from Descovy are manageable, but a few can be serious. Serious side effects of Descovy include lactic acidosis (buildup of lactic acid in the blood) and liver problems. (See the WARNING box above.)
Other possible side effects of Descovy include:
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of Descovy. To learn more about possible side effects of Descovy, read the drug label or package insert or talk to your health care provider or pharmacist.
The AIDSinfo fact sheet on HIV Medicines and Side Effects also includes information that may apply to Descovy.
You can also report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online at https://www.accessdata.fda.gov/scripts/medwatch/.
More information about Descovy is available:
Gilead Sciences, Inc.
Main number: 800-445-3235
Patient assistance: 800-226-2056
Last Reviewed: March 13, 2017