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Zoster Vaccine Recombinant, Adjuvanted

Zoster Vaccine Recombinant, Adjuvanted

Brand Name: Shingrix Other Names: RZV, recombinant Varicella Zoster Virus (VZV) glycoprotein E, recombinant shingles vaccine, recombinant zoster vaccine Drug Class: Opportunistic Infections and Coinfections
What is Shingrix?

What is Shingrix?

Shingrix is a vaccine approved by the U.S. Food and Drug Administration (FDA) to prevent herpes zoster (shingles) in adults 50 years of age and older. Herpes zoster occurs when latent varicella zoster virus (VZV) infection becomes reactivated in the body. VZV infection is an opportunistic infection (OI) of HIV. An OI is an infection that occurs more frequently or is more severe in people with weakened immune systems—such as people with HIV—than in people with healthy immune systems. To learn more about OIs, read the AIDSinfo What is an Opportunistic Infection? fact sheet.

The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents with HIV include recommendations on the use of Shingrix in people with HIV.

What should I tell my health care provider before receiving Shingrix?

What should I tell my health care provider before receiving Shingrix?

Before receiving Shingrix, tell your health care provider:

  • If you are allergic to yeast, any ingredients in Shingrix, or any medicines. Tell your health care provider if you have ever had any reactions to a previous dose of the Shingrix vaccine.
  • About any medical conditions you have or have had.
  • About any health conditions that may prevent you from receiving medicine by injection or infusion.
  • If you are pregnant or plan to become pregnant. Talk to your health care provider about the risks and benefits of getting a Shingrix vaccine during pregnancy.
  • If you are breastfeeding or plan to breastfeed. Do not breastfeed if you have HIV.
  • About other prescription and nonprescription medicines, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Shingrix may affect the way other medicines or products work, and other medicines or products may affect how Shingrix works. Ask your health care provider if there are interactions between Shingrix and the medicines you take.

Ask your health care provider about possible side effects from getting a Shingrix vaccine. Your health care provider will tell you what to do if you have side effects.

How is Shingrix given?

How is Shingrix given?

A health care provider gives the Shingrix vaccine. The vaccine is given as a shot. Vaccination with Shingrix is usually given as a series of two vaccine shots over a 6-month period. Read any printed information that your health care provider gives you about the Shingrix vaccine.

Where can I find more information about Shingrix vaccines?

Where can I find more information about Shingrix vaccines?

More information about Shingrix vaccines is available:

The above Patient Version drug summary is based on the following FDA label(s): Injection.

Last Reviewed: September 11, 2019

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