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Issue No. 51 | December 7, 2007

News and Features

Comments Welcome on the Updated Adult and Adolescent Treatment Guidelines

Don't forget, the latest version of the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents was released on December 1. The updated guidelines are available for download from the Adult and Adolescent Guidelines section of AIDSinfo. You can also order them by mail or e-mail from AIDSinfo's Order Publications section.

Your Feedback is Important!

The Adult and Adolescent HIV Guidelines Working Group would like to hear your feedback on the latest revisions to the Adult and Adolescent Guidelines. Please send your comments with the subject line "Adult and Adolescent Comments" to by December 15, 2007.

HIV/AIDS Information is Available on Second Life

As a contribution to World AIDS Day 2007, the Specialized Information Services (SIS) Division of the National Library of Medicine (NLM) has created an HIV/AIDS exhibit in the virtual world of Second Life.

Second Life (SL) is a 3-D virtual world entirely created by its Residents. Since opening to the public in 2003, it has grown explosively and today is inhabited by millions of Residents from around the globe. (You have to be at least 18 years of age to join SL.)

The exhibit, located in the "SL Health Information Outreach Lab" parcel on Health Information Island, includes a display of NLM's, NIH's, and other government resources on HIV/AIDS. The exhibit allows SL users to access government Web sites with authoritative information about HIV/AIDS for patients, families, and the general public.

Featured Web sites include AIDSinfo, AIDSinfo en español (infoSIDA), NLM's AIDS Portal, MedlinePlus,,, and others. A number of national and international medical libraries collaborating on Health Information Island held special activities on December 1 in commemoration of World AIDS Day 2007.


New Drug Resistance Mutation Discovered

According to a new study, 1 out of every 10 HIV-infected people receiving drug treatment has a hidden genetic mutation that makes certain strains of the virus more resistant to antiretroviral medications. The mutation specifically affects the response to zidovudine and nevirapine.

The study suggests that it is necessary to test for this mutation when deciding on a drug regimen for a patient. The discovery of the mutation could also have implications for future anti-HIV drug development.

More information involving this discovery is available:

  • MedlinePlus: Full Story
  • AIDSinfo: Adult and Adolescent Treatment Guidelines (featuring updated drug resistance testing recommendations)
  • AIDSinfo: Zidovudine drug fact sheet
  • AIDSinfo: Nevirapine drug fact sheet