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Issue No. 2 | January 11, 2008

News and Features

Panel on Antiretroviral Guidelines for Adults and Adolescents Welcomes New Members!

The DHHS Panel on Antiretroviral Guidelines for Adults and Adolescents (a working group of the Office of AIDS Research Council) is pleased to welcome the following new members to the Panel. The new members will begin a 3-year term starting in February 2008:

  • Eric Daar, M.D. (University of California-Los Angeles, Harbor-UCLA Medical Center)
  • Gerald Friedland, M.D. (Yale School of Medicine)
  • Paul Sax, M.D. (Harvard Medical School & Brigham and Women's Hospital)
  • David Wohl, M.D. (University of North Carolina-Chapel Hill) 

The Panel thanks the following members, who will be concluding their services to the Panel, for their contributions over the years: 

  • Wafaa El-Sadr, M.D., M.P.H. (Columbia University)
  • Eric Goosby, M.D. (Pangaea Global AIDS Foundation & University of California-San Francisco; first co-convener of the Panel)
  • Mark Harrington (Treatment Action Group)
  • John Mellors, M.D. (University of Pittsburgh)
  • James Oleske, M.D., M.P.H. (University of Medicine and Dentistry of New Jersey)

The Adult and Adolescent Guidelines are available from AIDSinfo.

Study Finds Antidepressants Help HIV-Infected Individuals with Depression Comply with Treatment

A recently published study has demonstrated that HIV-infected individuals who are clinically depressed and take selective serotonin reuptake inhibitors (SSRIs), a class of commonly used antidepressants, are more likely to adhere to their antiretroviral regimen.

About 3,400 HIV-infected study participants were observed for 12 months. Participants with clinical depression (42%) were less likely to adhere to their treatment regimens and had poorer viral responses than participants who were not depressed. Participants with depression who took SSRIs as prescribed had better regimen adherence and had CD4 responses that were statistically similar to HIV-infected individuals without depression who received HAART.

Researchers concluded that adherence to SSRIs improves HAART adherence, leading to improved health outcomes in clinically depressed patients.

More information is available:

  • PubMed: Study abstract
  • AIDSinfo Health Topics: Mental Health
  • SAMHSA: Mental Health and HIV fact sheet