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Issue No. 49 | November 21, 2008

News and Features

NIAID: Early HIV Testing and Treatment Greatly Reduce Death and Illness in Infants

"A new study finalizes research that changed guidelines around the world regarding when HIV-infected babies should begin drug therapy. ... [S]urvival rates were greatly improved among those children who received early treatment. Infant mortality was reduced by 76 percent, and HIV progression by 75 percent, the study said. ... Death rates among those who got early treatment were similar to those among infants who weren't HIV-infected[.] ...

Early treatment not only combats HIV sooner, it has other positive effects, [study lead author Avy] Violari said. 'Early treatment protects the brain from HIV, so not only do they survive, but they are likely to have less developmental problems than other babies who didn't get early treatment[.]'"

Study: Cancer Risk Higher in HIV Infected

"People with HIV are at a much greater risk of developing certain cancers - including of the lung, liver, head, and neck - than the general population[.] ... The research, presented ... at the seventh annual American Association for Cancer Research International Conference on Frontiers in Cancer Prevention Research, found that people with HIV are twice as likely to develop several cancers not previously linked to the virus."

Study: NRTIs Induce Inflammation Tied to Diabetes

"Researchers ... say a new study may help explain why people taking certain AIDS drugs are more likely to develop diabetes and heart disease. Nucleoside reverse transcriptase inhibitors (NRTIs) ... trigger inflammation that can lead to the metabolic complications[.]"

Study: Analysis of Outcomes for AIDS-Presenting Patients

"OBJECTIVE: Many patients infected with HIV still present with an AIDS diagnosis. The aim of this study was to evaluate the virological, immunological and clinical outcomes of HAART in these patients. ... CONCLUSION: Virological suppression was achieved in most AIDS patients, though mortality remains high in these individuals."

Happy Thanksgiving from AIDSinfo!

AIDSinfo At-a-Glance will not be published next week due to the Thanksgiving holiday. We will resume publication the week of November 30.

We wish you and your family a safe and happy Thanksgiving!