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Issue No. 10 | February 27, 2009

News and Features

Updated Pediatric Treatment Guidelines: Your Feedback Is Important!

The Pediatric Antiretroviral Guidelines Working Group would like to hear your feedback on the latest revisions to the Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection and the updated Pediatric Antiretroviral Drug Information supplement.

Please send your comments with the subject line "Pediatric Comments" to by March 13, 2009.

FDA: People with Impaired Immune Systems Should Take Care with Peanut Products

"The Centers for Disease Control and Prevention (CDC) has been receiving reports of illnesses caused by a type of Salmonella called Salmonella Typhimurium, which have been traced to certain peanut products.

People with impaired immune systems, such as those with HIV/AIDS, are more likely to become severely ill from a Salmonella infection than are others. When severe infection occurs, Salmonella may spread from the intestines to the bloodstream and can even cause death unless properly treated.

Most persons infected with Salmonella develop diarrhea (sometimes bloody), vomiting, fever, and abdominal cramps within 12 to 72 hours after infection. Illness ranges from mild to severe. The illness usually lasts 4 to 7 days, and most people recover without treatment. However, infants, the elderly, and people with impaired immune systems are more likely to become severely ill from a Salmonella infection than are others.

If you have the symptoms listed above, see your health professional."

Study: HIV Continues to Evolve among Large Groups

"The AIDS virus is quickly adapting across large groups of people to avoid triggering the human immune system, posing another challenge in the search for a potential vaccine, researchers said on Wednesday.

Scientists know the human immunodeficiency virus, or HIV, constantly mutates within individual people to find ways to attack cells.

But the study published in the journal Nature suggests changes that help the virus do this are increasingly passed on in the wider population.

`What was previously clear is the virus could evolve within each infected person but that doesn't really matter from a vaccine perspective if the virus at the population level is staying the same,' said Philip Goulder, an immunologist at Oxford University who led the study."

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