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Issue No. 28 | June 26, 2009

News and Features

National HIV Testing Day is June 27, 2009

"The importance of National HIV Testing Day becomes clear when one recognizes that an estimated one-fifth of all Americans infected with HIV do not know they are infected. Among Americans who have been tested for the virus, more than one-third of those who learned they are infected became aware of their status less than a year before being diagnosed with AIDS -- long after the optimal time to begin antiretroviral therapy....The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, urges everyone ages 13 to 64 to get tested for HIV as part of their routine health care....People at high risk for HIV infection -- such as injection drug users, gay and bisexual men, female partners of bisexual men, and people with multiple sexual partners -- should get tested at least once a year."

FDA: Didanosine Label Changes

"[The] FDA recently approved new labeling for Videx pediatric powder and Videx EC capsules. [There are] revisions to the Dosage and Administration, Contraindications, Warnings and Precautions, and Drug Interactions sections.... Other minor changes to the package inserts were made for consistency. In addition the Videx pediatric powder package insert was converted to Physician Labeling Rule (PLR) format."

Study: Radical New Strategy Could Improve HIV/AIDS Treatment

"A radical new therapy could improve treatment of people with HIV-AIDS by destroying the viruses circulating in the body as well as those hiding in immune system cells, according to a new study.... A team of American and Canadian researchers have high hopes for a combination of targeted chemotherapy and what's known as highly active anti-retroviral (HAART) treatments."

Study: HIV Infection and Risk of Diabetes

"The influence of HIV infection on the risk of diabetes is unclear. ... We studied 3227 HIV-infected and 3240 HIV-uninfected individuals. HIV-infected individuals were younger, more likely to be black males, have HCV coinfection and a lower BMI. HIV-infected individuals had a lower prevalence of diabetes at baseline (14.9 vs. 21.4%, P < 0.0001). ... Although HIV infection itself is not associated with increased risk of diabetes, increasing age; HCV coinfection and BMI have a more profound effect upon the risk of diabetes among HIV-infected persons. Further, long-term ARV treatment also increases risk. Future studies will need to determine whether incidence of diabetes mellitus differs by HIV status."