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Issue No. 13 | April 2, 2010

News and Features

Spring 2010 Issue of mental health AIDS Is Released

The quarterly biopsychosocial research update on HIV and mental health, mental health AIDS, is sponsored by the Center for Mental Health Services (CMHS) of the Substance Abuse and Mental Health Services Administration (SAMHSA) and is disseminated free of charge through the SAMHSA Web site in both PDF and HTML formats.

The Spring 2010 issue features "HIV & Hepatitis C: Coping with Coinfection (Part 1)."

"There are an estimated 250,000 people living in the United States with HIV/hepatitis C (HCV) coinfection, yet less than a third of these individuals 'are deemed eligible for HCV treatment, and under 10% actually receive treatment. Without HCV treatment, increasing numbers of HIV-infected patients will die either from end-stage liver disease or from HIV-related complications resulting from the inability to use antiretroviral agents' because of liver damage.

"This is the first of a two-part series. Part 1 provides a medical, psychiatric, psychosocial, and neuropsychological overview of HIV/HCV coinfection, the process of determining eligibility for HCV treatment, and the important role mental health clinicians play in assessing eligibility and intervening with clients who elect to receive treatment for HCV. "

More information is available:

Study Suggests Antiretroviral Drug Resistance May Occur in HIV-Infected People with Low-Level Viremia

“This study characterized the prevalence and patterns of antiretroviral-drug-resistance mutations according to plasma human immunodeficiency virus type 1 (HIV-1) RNA load in a large population of patients with HIV-1 infection who underwent testing for resistance mutations in routine clinical practice. HIV-1 genotypic resistance test results with linked clinical data were obtained from national resistance and clinical databases in the United Kingdom. Among 7861 tests, detection of 1 resistance mutation was most frequent at viral loads of 300-10,000 copies/mL and decreased statistically significantly at viral loads of >10,000 copies/mL. Major resistance mutations were commonly detected in the subset of tests that were performed among patients with viral loads of <1000 copies/mL (1001 [12.7%] of 7861 tests). We conclude that HIV-1 genotypic resistance testing is informative for patients with low viral loads.”

More information is available: