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Issue No. 34 | August 16, 2010

News and Features

Updated HHS Pediatric Antiretroviral Treatment Guidelines Now Available

AIDSinfo announces the release of the updated Guidelines for the Use of Antiretroviral Agents in Pediatric Infection. Key updates and new information included in the guidelines are prefaced in What’s New in the Pediatric Guidelines? Additions and revisions are also highlighted in yellow throughout the text and tables of the guidelines.

Key updates to the guidelines include:

  • A ratings system to indicate strength and quality of evidence for each major recommendation.
  • A single appendix combining information from the previous Appendix B (Characteristics of Available Antiretroviral Drugs) and Supplement I (Pediatric Antiretroviral Drug Information). The information for each antiretroviral drug is summarized in a table-with-text format in the current Appendix B: Pediatric Antiretroviral Drug Information.
  • Information from previous Supplement III: Adverse Drug Effects is now included in the body of the guidelines in table format.
  • New information or key changes to recommendations in several sections of the guidelines including Diagnosis of HIV Infection in Infants, When to Initiate Therapy, What Drugs to Start, and Adherence to Antiretroviral Therapy in HIV-Infected Children and Adolescents.
  • Addition of updated references throughout the guidelines.

The updated guidelines and separate PDF files of the tables in the guidelines can be downloaded from the Pediatric Guidelines section of AIDSinfo. You may also go to the AIDSinfo Order Publications page to request the guidelines via e-mail.

Your Feedback Is Important
The HHS Panel on Antiretroviral Therapy and Medical Management of HIV-Infected Children welcomes feedback on the latest revisions to the Guidelines for the Use of Antiretroviral Agents in Pediatric Infection. Please send your comments with the subject line "Comments on Pediatric Guidelines" to by August 30, 2010.