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Issue No. 27 | June 29, 2012

News and Features

Literature Review Examines Incidence of MRSA Infections Among HIV-Infected People

“Despite the rise of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) among HIV-infected persons during the era of highly active antiretroviral therapy (HAART), the precise relationship between these two infections has not been fully elucidated. Therefore, we provide a comprehensive, literature-based review of MRSA infections among HIV-infected persons. …

“A systematic search of MEDLINE using the search terms 'HIV' and 'MRSA' identified references published during the HAART era (January 1996 to January 2011). …

“The most common type of MRSA infection among HIV-infected persons is SSTI caused by USA300, Panton-Valentine leukocidin (PVL)-positive strains. HIV-infected persons have an increased risk for both initial MRSA infections and recurrent infections compared with the general population. Risk factors for MRSA infections in this population include immunosuppression, comorbid conditions and certain lifestyle behaviours such as high-risk sexual behaviours and illicit drug use. Further research is needed on the optimal treatment and prevention strategies for MRSA infections among HIV-infected persons. …

“HIV-infected persons have a propensity for MRSA SSTI and a high rate of recurrent disease. The reasons for the elevated rates of MRSA infections among HIV-infected persons appear to be multifactorial, but may be mitigated with optimized HIV control and reductions in associated risk factors.”

More information is available:

Visit infoSIDA for Spanish-Language HIV/AIDS Information

Are you looking for easy-to-understand HIV/AIDS treatment and research information in Spanish? Visit infoSIDA, the AIDSinfo Spanish-language sister site. The sites offer similar information, including a Glossary of HIV/AIDS-Related Terms and fact sheets about HIV. Visitors to infoSIDA can use a clinical trials search tool to locate HIV/AIDS research studies in which to participate. The site also provides links to other government HIV/AIDS-related resources.

For on-the-go access to Spanish-language HIV/AIDS information, check out the infoSIDA mobile site.