News and Features
HHS Antiretroviral Guidelines Panels Issue Recommendations Regarding the Use of Dolutegravir in Adults and Adolescents With HIV Who Are Pregnant or of Child-Bearing Potential
A National Institutes of Health (NIH)-funded observational surveillance study of birth outcomes among pregnant women on antiretroviral therapy (ART) in Botswana identified neural tube defects (NTDs) in four infants born to 426 women who initiated a dolutegravir (DTG)-based regimen prior to pregnancy, and who were still receiving it at the time of conception. This study is ongoing, and more data from approximately 600 additional births among pregnant women who have been using a DTG-based regimen from conception are expected in the next 9 months. Importantly, the same study presented data on women who initiated ART during the first trimester of pregnancy, and no NTDs were identified in the infants of the 116 women who initiated a DTG-based regimen in the first trimester or in 396 women who initiated an efavirenz (EFV)-based regimen. In the upcoming months, data from this study and other investigations will provide more information about the safety of DTG for infants exposed in utero.
The Department of Health and Human Services (HHS) Antiretroviral Guidelines Panels are issuing these recommendations to elaborate on our previous statement of May 18, 2018, and to support the related Food and Drug Administration (FDA) Drug Safety Communication.
For more information and to view the recommendations, visit the AIDSinfo website.
AIDSinfo Updates Consumer Fact Sheets on HIV Prevention
The updated AIDSinfo consumer fact sheets provide important information on HIV prevention. Each fact sheet includes a summary of key points and links to additional information and resources.
View the updated fact sheets:
- The Basics of HIV Prevention
- Preventing Mother-to-Child Transmission of HIV
- Post-Exposure Prophylaxis (PEP)
- Pre-Exposure Prophylaxis (PrEP)
Visit infoSIDA to view the fact sheets in Spanish.
Adult and Adolescent Opportunistic Infections Guidelines Updated
On May 29, updates to the following sections of the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents were published:
June 5 is HIV Long-Term Survivors Day
The Centers for Disease Control and Prevention (CDC) estimates that 1.1 million people in the United States were living with HIV at the end of 2015. A lot of these people have been living with HIV for many years. June 5 is a day set aside to honor HIV long-term survivors and to raise awareness of their needs and issues. To learn more, visit the AIDSinfo HIV Long-Term Survivors Day webpage [en español].