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Reverse Transcriptase (RT) Audio


An enzyme found in HIV (and other retroviruses). HIV uses reverse transcriptase (RT) to convert its RNA into viral DNA, a process called reverse transcription. Non-nucleoside reverse transcriptase inhibitors (NNRTIs) prevent HIV from replicating by blocking RT.

See Related Term(s): Life Cycle, Non-Nucleoside Reverse Transcriptase Inhibitor, Reverse Transcription

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Reverse transcription is the third step of HIV replication.

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