Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV

The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations.

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Management of the Treatment-Experienced Patient

Exposure-Response Relationship and Therapeutic Drug Monitoring (TDM) for Antiretroviral Agents

Last Updated: April 8, 2015; Last Reviewed: April 8, 2015

Panel's Recommendations Regarding Exposure-Response Relationship and Therapeutic Drug Monitoring (TDM) for Antiretroviral Agents
Panel's Recommendations
  • Therapeutic drug monitoring (TDM) for antiretroviral agents is not recommended for routine use in the management of patients with HIV (BII).
  • TDM may be considered in selected clinical scenarios, as discussed in the text below.
Rating of Recommendations: A = Strong; B = Moderate; C = Optional
Rating of Evidence: I = Data from randomized controlled trials; II = Data from well-designed nonrandomized trials or observational cohort studies with long-term clinical outcomes; III = Expert opinion

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