Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV

The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations.

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Limitations to Treatment Safety and Efficacy

Cost Considerations and Antiretroviral Therapy

Last Updated: October 17, 2017; Last Reviewed: October 17, 2017

Table 16. Monthly Average Wholesale Pricea of Commonly Usedb Antiretroviral Drugs
ARV Drug
(Generic and Brand Names)
Strength, Formulation Dosing Tablets, Capsules, or
mLs per Monthc
AWPa
(Monthly)
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
Abacavir
  • Generic
300 mg tablet 2 tablets daily 60 tablets $502.22–$603.33
  • Ziagen
300 mg tablet 2 tablets daily 60 tablets $670.37
  • Ziagen
20 mg/mL solution 30 mL daily 900 mL $660.86
Emtricitabine
  • Emtriva
200 mg capsules 1 capsule daily 30 capsules $643.82
  • Emtriva
10 mg/mL solution 24 mL daily 680 mL (28-day supply) $608.16
Lamivudine
  • Generic
300 mg tablet 1 tablet daily 30 tablets $324.33–$429.66
  • Epivir
300 mg tablet 1 tablet daily 30 tablets $498.89
  • Epivir
10 mg/mL solution 30 mL daily 900 mL $498.90
Tenofovir Disoproxil Fumarate
  • Viread
300 mg tablet 1 tablet daily 30 tablets $1,279.94
Zidovudine
  • Generic
300 mg tablet 1 tablet twice daily 60 tablets $54.00–$365.44
NRTI Combination Products
Abacavir/Lamivudine
  • Generic
600/300 mg tablets 1 tablet daily 30 tablets $1,395.00
  • Epzicom
600/300 mg tablets 1 tablet daily 30 tablets $1,550.05
Tenofovir Alafenamide/Emtricitabine
  • Descovy
 25/200 mg tablet 1 tablet daily
30 tablets $1,881.14
Tenofovir Disoproxil Fumarate/Emtricitabine
  • Truvada
300/200 mg tablet 1 tablet daily 30 tablets $1,881.14
Zidovudine/Lamivudine
  • Generic
300/150 mg tablet 1 tablet twice daily 60 tablets $877.85–$931.61
  • Combivir
300/150 mg tablet 1 tablet twice daily 60 tablets $1,081.70
Abacavir Sulfate/Zidovudine/Lamivudine
  • Generic
300/300/150 mg tablet 1 tablet twice daily 60 tablets $1,738.46
  • Trizivir
300/300/150 mg tablet 1 tablet twice daily 60 tablets $1,931.64
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
Efavirenz
  • Sustiva
600 mg tablet 1 tablet daily 30 tablets $1,176.74
Etravirine
  • Intelence
200 mg tablet 1 tablet twice daily 60 tablets $1,411.42
Nevirapine
  • Generic
200 mg tablet 1 tablet twice daily 60 tablets $648.19–$650.70
  • Viramune
200 mg tablet 1 tablet twice daily 60 tablets $967.63
  • Viramune XR
400 mg tablet 1 tablet daily 30 tablets $897.46
Rilpivirine
  • Edurant
25 mg tablet 1 tablet daily 30 tablets $1,160.10
Protease Inhibitors (PIs)
Atazanavir
  • Reyataz
200 mg capsule
2 capsules daily 60 capsules $1,755.91
  • Reyataz
300 mg capsuled 1 capsule daily  30 capsules $1,739.50
Atazanavir/Cobicistat
  • Evotaz
300/150 mg tablet 1 tablet daily 30 tablets $1,926.56
Darunavir
  • Prezista
600 mg tablete 1 tablet twice daily 60 tablets $1,757.77
  • Prezista
800 mg tabletd 1 tablet daily  30 tablets $1,757.77
  • Prezista
100 mg/mL suspensione 8 mL daily 240 mL $1,171.85
6 mL twice daily 360 mL $1,757.77
Darunavir/Cobicistat
  • Prezcobix
800/150 mg tablet 1 tablet daily 30 tablets $2,009.23
Lopinavir/Ritonavir
  • Kaletra
200/50 mg tablet 2 tablets twice daily
or
4 tablets once daily
120 tablets $1,160.50
  • Kaletra
80/20 mg per mL solution 5 mL twice daily 300 mL $1,087.97
Tipranavir
  • Aptivus
250 mg capsulee 2 capsules twice daily 120 capsules $1,786.73
Integrase Strand Transfer Inhibitors (INSTIs)
Dolutegravir
  • Tivicay
50 mg tablet
1 tablet once daily
30 tablets $1,842.82
  • Tivicay
50 mg tablet
1 tablet twice daily
60 tablets $3,685.64
Raltegravir
  • Isentress
400 mg tablet 1 tablet twice daily 60 tablets $1,667.52
  • Isentress HD
600 mg tablet 2 tablets once daily 60 tablets $1,667.52
Fusion Inhibitor
Enfuviritide
  • Fuzeon
90 mg injection kit 1 injection twice daily 60 doses (1 kit) $4,302.67
CCR5 Antagonist
Maraviroc
  • Selzentry
150 mg tablet 1 tablet twice daily 60 tablets $1,679.68
  • Selzentry
300 mg tablet 1 tablet twice daily 60 tablets $1,679.68
  • Selzentry
300 mg tablet 2 tablets twice daily
120 tablets $3,359.36
Coformulated Combination Products as Single Tablet Regimens
Dolutegravir/Abacavir/Lamivudine
  • Triumeq
50/600/300 mg tablet 1 tablet daily 30 tablets $3,118.62
Efavirenz/Tenofovir Disoproxil Fumarate/Emtricitabine
  • Atripla
600/300/200 mg tablet 1 tablet daily 30 tablets $3,057.89
Elvitegravir/Cobicistat/Tenofovir Alafenamide/Emtricitabine
  • Genvoya
150/150/10/200 mg tablet 1 tablet daily
30 tablets $3,306.92
Elvitegravir/Cobicistat/Tenofovir Disoproxil Fumarate/Emtricitabine
  • Stribild
150/150/300/200 mg tablet 1 tablet daily 30 tablets $3,707.99
Rilpivirine/Tenofovir Alafenamide/Emtricitabine
  • Odefsey
25/25/200 mg tablet 1 tablet daily 30 tablets $3,009.29
Rilpivirine/Tenofovir Disoproxil Fumarate/Emtricitabine
  • Complera
25/300/200 mg tablet 1 tablet daily 30 tablets $3,216.92
Pharmacokinetic Enhancers (Boosters)
Cobicistat
  • Tybost
150 mg tablet 1 tablet daily 30 tablets $246.84
Ritonavir: Total daily dose depends on the dose of the concomitant PI (100 mg once or twice daily, or 200 mg twice daily)
  • Norvir

100 mg tablet 1 tablet once daily 30 tablets $308.60
  • Norvir
80 mg/mL solution 100 mg daily 37.5 mL (of a 240 mL bottle) $270.04
a AWP = average wholesale price. Note that the AWP may not represent the pharmacy acquisition price or the price paid by public and private payors or consumers. Source: http://www.micromedexsolutions.com. Accessed September 2017.
b The following less commonly used ARV drugs are not included in this table: delavirdine, didanosine, fosamprenavir, indinavir, nelfinavir, saquinavir, and stavudine.
c Represents 30 days or as specified.
d Should be used in combination with ritonavir or cobicistat. Please refer to Appendix B, Table 3 for ritonavir doses.
e Should be used in combination with ritonavir. Please refer to Appendix B, Table 3 for ritonavir doses.

Key to Acronyms: ARV = antiretroviral; XR = extended release

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