Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents
The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations.
Human Herpesvirus-8 Disease
Last Updated: May 29, 2018; Last Reviewed: February 21, 2018
|Preventing Development of KS
All patients with MCD should receive ART (AIII) in conjunction with one of the therapies listed below.
Therapy Options (in consultation with a specialist, and depending on HIV/HHV-8 status, presence of organ failure, and refractory nature of disease):
|Key to Acronyms: ART = antiretroviral therapy; BID = twice daily; IV = intraveneously; KS = Kaposi sarcoma; MCD = multicentric Castleman’s disease; PEL = primary effusion lymphoma; PO = orally; q(n)h = every ”n” hours
1 The commonly used AIDS Clinical Trials Group (ACTG) KS Staging Classification uses T(Tumor), Immune(I), and Systemic illness (S) criteria to classify patients into ”Good Risk” and ”Poor Risk” categories (ref Krown, JCO, 1989). ”Good Risk” tumor stage criteria are used by some specialists to correspond with mild-to-moderate KS.
- CDC | 2015 STD Treatment Guidelines
- HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C
- AIDSinfo Patient Materials: What is an Opportunistic Infection?
- AIDSource | HIV-Related Conditions
- AETC National HIV Curriculum
- How to Cite These Guidelines
- Adult and Adolescent OI Guidelines Archive