HHS Panel on Antiretroviral Guidelines for Adults and Adolescents Includes a Fixed-Dose Combination of Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Among the Recommended Regimens for Antiretroviral Treatment-Naive Individuals with HIV-1 Infection
(Last updated: January 29, 2008; last reviewed: April 8, 2015)
|Generic Name (Abbreviation)/ Trade Name||Formulation||Dosing Recommendation||Serum Half-Life||Elimination||Storage||Adverse Eventsa
||90 mg (1mL) subcutaneously BID||3.8 hours||Expected to undergo catabolism to its constituent amino acids, with subsequent recycling of the amino acids in the body pool
||Store at room temperature (up to 25º C or 77º F). Re-constituted solution should be refrigerated at 2º to 8º C (36º to 46º F) and used within 24 hours.
|a Also see Table 14.
Key to Abbreviations: BID = twice daily; HSR = hypersensitivity reaction; T20 = enfuvirtide