The Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents have been updated!
Revisions are largely based on findings from two large, randomized controlled trials that addressed the optimal time to initiate ART -- START and TEMPRANO.
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(Last updated: January 29, 2008; last reviewed: April 8, 2015)
|Generic Name (Abbreviation)/ Trade Name||Formulation||Dosing Recommendation||Serum Half-Life||Elimination||Storage||Adverse Eventsa|
||90 mg (1mL) subcutaneously BID||3.8 hours||Expected to undergo catabolism to its constituent amino acids, with subsequent recycling of the amino acids in the body pool
||Store at room temperature (up to 25º C or 77º F). Re-constituted solution should be refrigerated at 2º to 8º C (36º to 46º F) and used within 24 hours.
|a Also see Table 14.
Key to Abbreviations: BID = twice daily; HSR = hypersensitivity reaction; T20 = enfuvirtide