(Last updated: March 5, 2015; last reviewed: March 1, 2016)
The care of HIV-infected children is complex and evolving rapidly as results of new research are reported, new antiretroviral (ARV) drugs are approved, and new approaches to treatment are recommended. Clinical trials to define appropriate drug dosing and toxicity in children ranging in age from infancy to adolescence are critical as new drugs become available. As additional ARV drugs become approved and optimal strategies for use of these drugs in children becomes better understood, the Panel will modify these guidelines. These guidelines are only a starting point for medical decision-making and are not meant to supersede the judgment of clinicians experienced in the care of HIV-infected children. Because of the complexity of caring for HIV-infected children, and the decreasing number of children with perinatally acquired HIV in the United States, health care providers with limited experience in the care of these patients should consult with a pediatric HIV specialist.
The Centers for Disease Control and Prevention, the National Institutes of Health, the HIV Medicine Association, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the American Academy of Pediatrics jointly developed and published guidelines for the prevention and treatment of opportunistic infections in HIV-exposed and HIV-infected children; these guidelines are available at https://aidsinfo.nih.gov.1 Similar guidelines for adults are also available at the same website.2