Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection
The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations.
Brief Version (N/A)
Appendix B: Acronyms
General Terms
Last Updated: April 16, 2019; Last Reviewed: April 16, 2019
Acronym | Term |
---|---|
°C | degrees Celsius |
°F | degrees Fahrenheit |
AE | adverse effect |
ALP | alkaline phosphatase |
ALT | alanine aminotransferase |
ANC | absolute neutrophil count |
APHL | Association of Public Health Laboratories |
ART | antiretroviral therapy |
ARV | antiretroviral |
AST | aspartate aminotransferase |
AUC | area under the curve |
AUC0-12h | area under the curve at 12 hours post-dose |
AUC24h | area under the curve at 24 hours post-dose |
AV | atrioventricular |
BCRP | breast cancer resistance protein |
BMD | bone mineral density |
BMI | body mass index |
BSA | body surface area |
C0h | pre-dose concentration |
C12 or C12h | mid-dose concentration |
CBC | complete blood count |
CD4 | CD4 T lymphocyte |
CDC | Centers for Disease Control and Prevention |
CI | confidence interval |
CK | creatine kinase |
Cmax | maximum plasma concentration |
Cmin | minimum plasma concentration |
CMV | cytomegalovirus |
CNS | central nervous system |
CrCl | creatinine clearance |
CT | continuous therapy |
CV | coefficients of variation |
CVD | cardiovascular disease |
CYP | cytochrome P |
dL | deciliter |
DM | diabetes mellitus |
DMPA | depot medroxyprogesterone acetate |
DNA | deoxyribonucleic acid |
DOT | directly observed therapy |
DRESS | drug reaction (or rash) with eosinophilia and systemic symptoms |
DSMB | Data Safety Monitoring Board |
DXA | dual energy x-ray absorptiometry |
EBV | Epstein-Barr virus |
EC | enteric-coated |
ECG or EKG | electrocardiogram |
EEG | electroencephalogram |
eGFR | estimated glomerular filtration rate |
EM | erythema multiforme or extensive metabolizers |
EMA | European Medicines Agency |
FDA | Food and Drug Administration |
FDC | fixed-dose combination |
fL | femtoliter |
fmol | femtomole |
FLP | fasting lipid profile |
FPG | fasting plasma glucose |
G6PD | glucose-6-phosphate dehydrogenase |
GFR | glomerular filtration rate |
GI | gastrointestinal |
GM | geometric mean |
HAV | hepatitis A virus |
HBV | hepatitis B virus |
HCV | hepatitis C virus |
HDL-C | high-density lipoprotein cholesterol |
Hgb | hemoglobin |
HgbA1c | glycosylated hemoglobin |
HHS | Department of Health and Human Services |
HIV RNA or HIV-1 RNA | viral load |
HLA | human leukocyte antigen |
HPV | human papilloma virus |
HRSA | Health Resources and Services Administration |
HSR | hypersensitivity reaction |
HSV | herpes simplex virus |
IAS-USA | International Antiviral Society-USA |
ICH | intracranial hemorrhage |
INH | isoniazid |
INSTI | integrase strand transfer inhibitor |
IQ | inhibitory quotient |
IQR | interquartile range |
IRIS | immune reconstitution inflammatory syndrome |
IU | international units |
IV | intravenous |
IVIG | intravenous immune globulin |
kg | kilogram |
L | liter |
LDL | low-density lipoprotein |
LDL-C | low-density lipoprotein cholesterol |
LFT | liver function test |
LLD | lower level of detection |
LLQ | lower limits of quantitation |
LS | lipodystrophy syndrome |
mcg or μg | microgram |
MCV | mean cell volume |
mg | milligram |
min | minute |
mL | milliliter |
mm | millimeter |
NASBA | nucleic acid sequence-based amplification |
NAT | nucleic acid test |
ng | nanogram |
NHLBI | National Heart, Lung, and Blood Institute |
NIH | National Institutes of Health |
NNRTI | non-nucleoside reverse transcriptase inhibitor |
NRTI | nucleoside reverse transcriptase inhibitor |
NTD | neural tube defect |
OARAC | Office of AIDS Research Advisory Council |
OBT | optimized background therapy |
OGTT | oral glucose tolerance test |
OI | opportunistic infection |
oz | ounce |
PBMC | peripheral blood mononuclear cell |
PCP | Pneumocystis jirovecii pneumonia |
PCR | polymerase chain reaction |
PEP | post-exposure prophylaxis |
PG | plasma glucose |
P-gp | P-glycoprotein |
PI | protease inhibitor |
PK | pharmacokinetic |
PPI | proton pump inhibitor |
PUFA | polyunsaturated fatty acid |
py | patient years |
QTc | corrected QT |
RBV | ribavirin |
RNA | ribonucleic acid |
RPG | random plasma glucose |
RT-PCR | reverse transcription polymerase chain reaction |
SCT | short-cycle therapy |
SD | standard deviation |
SDD | study drug discontinuation |
SJS | Stevens-Johnson syndrome |
SM | slow metabolizers |
SMR | sexual maturity rating |
SQ | subcutaneous |
STI | sexually transmitted infection |
T½ | half-life |
TB | tuberculosis |
TC | total cholesterol |
TDM | therapeutic drug monitoring |
TEN | toxic epidermal necrolysis |
TFV | tenofovir |
TFV-DP | tenofovir diphosphate |
TG | triglyceride |
THAM | tris (hydroxymethyl) aminomethane |
Tmax | time to reach maximum concentration |
TMP-SMX | trimethoprim sulfamethoxazole |
UGT | uridine diphosphate glucuronosyltransferase |
ULN | upper limit of normal |
VLS | viral load suppression |
WHO | World Health Organization |
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