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Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection

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Management of Children Receiving Antiretroviral Therapy

Overview

Last Updated: March 1, 2016; Last Reviewed: March 1, 2016

In the United States, the majority of HIV-infected children are receiving antiretroviral therapy (ART), making treatment-experienced children the norm. Changes in the antiretroviral (ARV) regimen and other aspects of the management of treatment-experienced children can be organized into the following categories:

  1. Modifying ARV regimens in children on effective ART for simplification or improved adverse effect profile;
  2. Recognizing and managing ARV drug toxicity or intolerance (see Management of Medication Toxicity or Intolerance);
  3. Recognizing and managing treatment failure; and
  4. Considerations about interruptions in therapy.

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