CCR5 Definition

CCR5

Synonym(s): C-C Chemokine Receptor 5, Cysteine-Cysteine Chemokine Receptor 5

A protein on the surface of certain immune system cells, including CD4 T lymphocytes (CD4 cells). CCR5 can act as a coreceptor (a second receptor binding site) for HIV when the virus enters a host cell.

Related Term(s): CCR5 Antagonist, Coreceptor, Fusion, Life Cycle

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HIV binds to a host CD4 cell via coreceptors.

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HIV/AIDS Glossary