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HIV/AIDS Glossary

CCR5 Antagonist

Synonym(s): CCR5 Inhibitor, CCR5 Receptor Blocker

Antiretroviral (ARV) HIV drug class. CCR5 antagonists block the CCR5 coreceptor on the surface of certain immune cells, such as CD4 T lymphocytes (CD4 cells). This prevents HIV from entering the cell.

Related Term(s): CCR5, Drug Class

Image(s):

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CCR5 antagonists prevent attachment.
Binding is the first step of HIV replication.

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