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HIV/AIDS Glossary

Optimized Background Therapy (OBT)

When a new drug is added to a failing HIV regimen, the other drugs in the regimen (the "background therapy") may also be changed. Any changes are made on the basis of a person’s resistance test results and treatment history. Optimized background therapy gives a new HIV regimen (or an experimental HIV drug being studied in a clinical trial) the best chance of succeeding.

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