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HIV/AIDS Glossary

Structured Treatment Interruption (STI)

Synonym(s): Drug Holiday

A planned break from treatment, during which a person stops taking medications. Structured treatment interruptions (STIs) may be used to reduce toxic effects of medications, to enhance a medication’s effectiveness when restarted, or as a step towards stopping treatment all together. Structured interruption of HIV treatment is not recommended outside of controlled clinical trials.

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