HIV/AIDS Glossary

Structured Treatment Interruption

Synonym(s): Drug Holiday

A planned break from treatment, during which a person stops taking medications. Structured treatment interruptions may be used to reduce toxic effects of medications, to enhance a medication’s effectiveness when restarted, or as a step towards stopping treatment altogether. Testing of an investigational HIV drug may include a structured treatment interruption to evaluate how long the drug continues to control a participant's viral load during the treatment break. Structured interruption of HIV treatment is not recommended outside of controlled clinical trials.

Related Term(s): Investigational Drug

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