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HIV/AIDS Glossary

gp120

Synonym(s): Glycoprotein 120, HIV Viral Envelope Glycoprotein 120

A glycoprotein on the HIV envelope. gp120 binds to a CD4 receptor on a host cell, such as a CD4 T lymphocyte (CD4 cell). This starts the process by which HIV fuses its viral membrane with the host cell membrane and enters the host cell.

Related Term(s): Envelope, Fusion, Glycoprotein, Life Cycle

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