HIV/AIDS Glossary

Vacuolar Myelopathy

A neurological disorder associated with advanced HIV infection. Vacuolar myelopathy causes the protective myelin sheath to pull away from nerve cells of the spinal cord, forming small holes (vacuoles) in nerve fibers. Symptoms of vacuolar myelopathy include weak and stiff legs and unsteadiness when walking.

Related Term(s): Myelin

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