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HIV/AIDS Glossary

Fusion

The second of seven steps in the HIV life cycle. After HIV attaches itself to a host CD4 cell, the HIV viral envelope fuses with the CD4 cell membrane. Fusion allows HIV to enter the CD4 cell. Once inside the CD4 cell, the virus releases HIV RNA and HIV enzymes, such as reverse transcriptase and integrase.

Related Term(s): Fusion Inhibitor, Life Cycle

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Fusion is step two of the HIV lifecycle.
Steps of HIV replication

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