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HIV/AIDS Glossary

Reverse Transcription

The third of seven steps in the HIV life cycle. Once inside a CD4 cell, HIV releases and uses reverse transcriptase (an HIV enzyme) to convert its genetic material—HIV RNA—into HIV DNA. The conversion of HIV RNA to HIV DNA allows HIV to enter the CD4 cell nucleus and combine with the cell’s genetic material—cell DNA.

Related Term(s): Life Cycle, Non-Nucleoside Reverse Transcriptase Inhibitor, Nucleoside Reverse Transcriptase Inhibitor, Reverse Transcriptase

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Reverse transcription is the third step of HIV replication.
Steps of HIV replication

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