HIV/AIDS Glossary

Protease Inhibitor (PI)

Antiretroviral (ARV) HIV drug class. Protease inhibitors (PIs) block protease (an HIV enzyme). By blocking protease, PIs prevent new (immature) HIV from becoming a mature virus that can infect other CD4 cells.

Related Term(s): Drug Class, Protease

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Protease inhibitors block HIV maturation.
Budding is step seven of HIV replication.

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