HIV/AIDS Glossary

PI-Sparing Regimen

Combination antiretroviral therapy (ART) that does not include antiretroviral (ARV) drugs from the protease inhibitor (PI) drug class. PIs may be excluded from an HIV treatment regimen to avoid certain side effects associated with this drug class, or to prevent the development of drug resistance to PIs so that a person with HIV can still use these drugs in future treatment regimens.