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HIV/AIDS Glossary

Nucleotide Reverse Transcriptase Inhibitor (NtRTI)

Synonym(s): Nucleotide Analogue Reverse Transcriptase Inhibitor

A type of antiretroviral (ARV) HIV drug. Nucleotide reverse transcriptase inhibitors (NtRTIs) interfere with the HIV life cycle in the same way as NRTIs. Both block reverse transcription. NtRTIs are included in the NRTI drug class.

Related Term(s): Drug Class, Nucleoside Reverse Transcriptase Inhibitor, Reverse Transcriptase, Reverse Transcription

Image(s):

(Click to enlarge)
Reverse transcription is the third step of HIV replication.
NNRTIs and NRTIs  block reverse transcription.

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